Complement Factor I Deficiency Associated With Recurrent Meningitis Coinciding With Menstruation
نویسندگان
چکیده
منابع مشابه
Complement factor B deficiency associated with recurrent asceptic meningitis
Background We report complement factor B deficiency in a 16-y-old Caucasian girl, who presented with recurrent episodes of aseptic meningitis. She presented with a 2-week history of headache, vomiting, neck stiffness, facial palsy, equilibrium problems, diplopia, and low grade temperature. 4 months prior to admission she presented with a leucocytoclastic vasculitis. MRI of the brain revealed gl...
متن کاملA family with complement factor I deficiency.
A family with inherited factor I deficiency is described. The proband was a 19-year-old Caucasian female with one episode of meningococcal meningitis and one episode of suspected septicaemia of unknown cause. Two obligate and two probable heterozygotes with factor I levels below the lower limit of the reference range were identified. None of these exhibited increased susceptibility to infectiou...
متن کاملHomozygous deficiency of the second component of complement presenting with recurrent bacterial meningitis.
A girl presented with purulent meningitis at ages 6, 8, and 11 years. She was in good health between these three episodes. When aged 16 one of her brothers also experienced an attack of pneumococcal meningitis. Complement studies showed lack of C2 in the patient and the brother, and intermediate values in the mother and a sister. No other member of the family was available for study.
متن کاملDeficiency of the eighth component of complement associated with recurrent meningococcal meningitis--case report and literature review.
The authors report a case of deficiency of the eighth component of complement in a young adult with a history of three episodes of meningitis; one of them proved to be meningococcal. The literature was reviewed and meningitis due to Neisseria meningitidis strains causing disease in complement-deficient and complement-sufficient patients was demonstrated. Meningococcal disease may be the first m...
متن کاملA family with complement factor D deficiency
The complement system consists of more than 20 plasma proteins and plays an important role in the defense against microorganisms (1). Activation of the classical or the alternative pathway results in the cleavage of C3, the central component of the system. In the alternative pathway, the spontaneous hydrolysis product iC3 (i.e., C3 with intact peptide chains but with a hydrolyzed thioester) com...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2001
ISSN: 0003-9942
DOI: 10.1001/archneur.58.11.1923